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| Use Case | Summary | PubMed Link |
|---|---|---|
| UTI Prevention & Anti-adhesion (E. coli) | Extensive clinical evidence indicates cranberry supplementation can help prevent UTIs. A 2023 review found cranberry products significantly reduced UTI incidence in susceptible groups. | |
| Antioxidant Effects | Cranberry extracts are rich in polyphenols with strong antioxidant activity. Studies demonstrate pronounced free radical scavenging properties of cranberry extract, reflecting high antioxidant potential. | PubMed |
| Bladder Mucosal Health | Research suggests cranberry supports a healthy bladder lining. In cell studies, cranberry extract protected urinary epithelial cells from UPEC bacterial damage—preserving cell viability and barrier integrity better than controls. | PubMed |
| Goal | Capsules per Day |
|---|---|
| UTI Prevention | 1 capsules daily (500 mg total), ideally once in the morning with food |
| Acute Support | 1 capsules twice daily (500 mg total) at first signs of UTI |
| Maintenance | 1 capsule daily on non-symptomatic days, for ongoing urinary tract support |
| Antioxidant & Mucosal Health | 1 capsule daily to maximize polyphenol intake and mucosal barrier protection |
NUTRITIONAL INFORMATION | |||
| Serving Size: 1 veg. Capsule | |||
| Amt. per Serving | % RDA Men | % RDA Women | |
| Cranberry Extract 25% (Vaccinium Oxycoccus) (Extract Ratio 15:1) | 500mg | ** | ** |
| Ingredients: Vaccinium Oxycoccus-fruit extract(Cranberry Extract), Bulking Agent INS 460 (i), Anticaking Agent (INS 551) & Vegetable Capsule Shell (HPMC) (INS 464). | |||
| Goal | Expected Timeline |
|---|---|
| UTI Incidence Reduction | 4–8 weeks of consistent use, with reductions seen by the second month of prevention |
| Anti-Adhesion Effect | Immediate—proanthocyanidins appear in urine within hours and inhibit adhesion |
| Antioxidant Status | 2–4 weeks to observe improved plasma antioxidant markers |
| Inflammation Modulation | 2–6 weeks for measurable reductions in urinary inflammatory cytokines |
| Mucosal Barrier Strength | 4–8 weeks to improve epithelial integrity, as indicated by reduced permeability markers |
| Goal | Synergistic Stack / Habit |
|---|---|
| UTI Prevention | Cranberry + D-mannose (500 mg twice daily) + adequate hydration (≥2 L/day) |
| Anti-Adhesion | Take cranberry 30 minutes before or after meals to concentrate PACs in the bladder |
| Antioxidant Support | Combine with Vitamin C (500 mg) and Vitamin E (200 IU) to boost overall antioxidant defense |
| Anti-Inflammatory | Add Omega-3 (1,000 mg EPA/DHA) or turmeric (curcumin 500 mg) for additional cytokine control |
| Bladder Health | Include a probiotic (Lactobacillus rhamnosus) to support a healthy urinary microbiome |
| Substance / Condition | Why to Avoid | Spacing Tip / Advice |
|---|---|---|
| High-Oxalate Diet | Cranberries are high in oxalates which may increase risk of kidney stones | Ensure adequate calcium intake and hydration; space high-oxalate meals 2 hrs from dosing |
| Antibiotics (Concurrent) | May alter urinary microbiome; limit overuse to necessary situations | Continue cranberry but consider timing 2–3 hrs apart from antibiotics |
| Caffeine & Alcohol | Can irritate bladder lining and counteract soothing mucosal effects | Avoid around dosing periods; stick to water or herbal teas |
| High-Sugar Juices | Sugar can feed pathogenic bacteria and negate benefits | Use unsweetened capsules; limit sugary beverages |
| Diuretics | May dilute cranberry compounds faster, reducing efficacy | Take cranberry 30 mins before diuretic to allow adequate absorption |
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